Please, stop looping over a dataframe

import pandas as pd
t = pd.DataFrame({'a': range(0, 100), 'b': range(0, 100)})

C = []
for i,r in t.iterrows():
    C.append((r['a'], r['b']))

C = []
for ir in t.itertuples():
    C.append((ir[1], ir[2]))

C = []
for r in zip(t['a'], t['b']):
    C.append((r[0], r[1]))

C = []
for r in zip(*t.to_dict("list").values()):
    C.append((r[0], r[1]))

result = [query_distance(conn, route, first_visit, last_visit)
          for route, first_visit, last_visit in zip(rs.RouteID, rs.FirstVisitTime, rs.LastVisitTime)]

ra_expanded.apply(lambda x: query_collected_bins(conn, x.RouteID, x.StartTime, x.EndTime), axis=1)

records = ra_expanded.loc[:,["RouteID", "StartTime", "EndTime"]].to_records()
[query_collected_bins(conn, int(x.RouteID), x.StartTime, x.EndTime) for x in records]

df['col_diff'] = df['col'] - df['col'].shift(1)

df['col_diff'] = df.col.diff()